Bethesda has released the Fallout 4 4.1.3 Update which brings in some fixes, tweaks, and even some new features to both game-play and Nvidia GameWorks effects.
Most notably is the addition of the FleX and HBAO+ effects. FleX will be used for weapon particle effects, but it is exclusively for certain Nvidia GPU’s. Meanwhile, HBAO+ is used to create realistic ambient occlusion shadows, and should be supported by both Nvidia & AMD GPU’s.
It appears these upgrades are specifically just for the PC version of the game, as the consoles run AMD chips, are cannot take advantage of GameWorks; though they do receive game-play related updates as usual.